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Gene-specific regularization for COPD partial-correlation estimation
We introduce a gene-specific regularization factor when computing the Partial Correlation score to make the indeterminate regression feasible. We decided to slightly modify... -
A New Topological Approach for the Prediction of Protein-Protein Interactions
We propose, Maximum-Proteins-Similarity(Topological)": MPS(T). MPS(T) is a topological three-length path method that scores the potential interaction between proteins by... -
A hybrid approach for PPI
We propose a new framework that can exploit topological and biological information to predict protein-protein interactions. The algorithm relies on the underlying hypothesis... -
EpiCID: A framework for discovering interactions between SNPs
Epistatic interactions (EIs) of gene loci often determine complex trait phenotypes. EIs may indicate the underlying molecular mechanisms of multifactorial traits and diseases....
